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Dr. Annie curtis

Annie Curtis has had a diverse career spanning academics, the public sector and industry.  

Annie conducted her PhD in the laboratory of Prof. Garret FitzGerald at University of Pennsylvania. This is where she was first introduced to the world of body clocks and uncovered mechanisms by which the clock controls cardiovascular function.

Annie spent time as a researcher in GlaxoSmithKline (GSK) in Philadelphia, a Scientific Programme Manager for Science Foundation Ireland (SFI) and a Medical Advisor for Immunotherapeutics with Bristol-Myers Squibb (BMS).

In 2011, she was given the opportunity by Prof. Luke O’Neill at Trinity College Dublin to return to academic research. In 2014, she was awarded an SFI Starting Investigator Research Grant (SIRG) to begin to establish an independent research group studying the impact of the body clock on the immune system.

She joined the Department of Molecular and Cellular Therapeutics and RCSI as a Research Lecturer in August 2016. In 2017, she was awarded the L’Oreal Women in Science Fellowship in 2017 and a Career Development Award from SFI.

Annie is a working mom of two little ladies, Lizzie and Faye. She is a supporter of STEM, and Women in Science. In the not too distant future she plans to read James Joyce's Ulysses, run a half marathon again, and cook something from her collection of cookbooks sitting on her kitchen shelf.



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Mariana P Cervantes Silva

Mariana obtained a Bachelor Degree in Bacteriology and Parasitology from the National Polytechnic Institute (IPN) in Mexico City (2011), and then worked as a researcher at the Angeles Hospital in Mexico City in the area of clinical immunology. In 2014 she obtained a Masters in Immunology from IPN, where she discovered the importance of mitochondria in the innate immune response.

Mariana began her PhD in Immunology in Mexico and for her last year she collaborated both with the Curtis laboratory at Royal College of Surgeons in Dublin and with the laboratory of Professor Luke O’Neill at Trinity College Dublin to complete her PhD.

She is now a postdoctoral researcher with the Curtis laboratory and her work focuses on unravelling the impact of mitochondria on the immune clock. She has presented her work at different congresses world wide and combines her scientific life with her other job of looking after her young family.


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george timmons

George obtained a Bachelor of Science degree in Human Health & Disease from Trinity College Dublin in 2016 and then worked briefly as a research assistant in the area of neuroimmunology before deciding to pursue a PhD.

George began his PhD in October 2016 and his project is focused on characterizing the metabolic phenotype of clock-disrupted immune cells and the effect this has on the inflammatory state.

He has a keen interest in health & fitness and when not in the lab he can usually be found in the gym or outside. He is also the resident foodie of the Curtis Lab, knowing the best places in Dublin for a bite to eat, coffee, or cocktails.



Past Alumni

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Cathy Wyse

Cathy Wyse was awarded a PhD from the University of Glasgow in 2003 and spent the next 10 years working as a postdoctoral researcher at the University of Bristol, Swansea and Aberdeen, before returning to Glasgow in 2013 as a Lord Kelvin-Adam Smith research fellow, and then joining the Curtis lab in RCSI in 2016. 

Cathy's research interests are focused on understanding the effects of disruption of circadian rhythms on physiology and behaviour, and their implications for human health and well-being. She has over 40 peer-reviewed publications and has presented her work at conferences all over the world.



james o. early

Jamie obtained his Bachelors degree in Genetics from the Smurfit institute of Genetics, Trinity College Dublin in 2014. It was here in the lab of Dr. Matthew Campbell that he became interested in the underlying mechanisms of inflammation and first discovered the subject of circadian rhythms.

Jamie began his PhD in Circadian innate immunity in the lab of Professor Luke O’ Neill in the Trinity Biomedical Sciences Institute under the supervision of Dr. Annie Curtis.

He is now in his final year of postgraduate study sharing time between both the O’ Neill lab in Trinity and Curtis lab in Royal College of Surgeons where he focuses on establishing the link between the circadian clock, antioxidant defense and inflammation.

Jamie has presented his work at several national and international conferences and forums, winning best speaker on three separate occasions. When not in the lab, Jamie enjoys his life as an undiscovered musical treasure in a very unsuccessful band.